Chemical Studies on Japanese Coccidae. XIV

Chemical biology studies on norrisolide.

The cellular activity of norrisolide (7), a novel Golgi-vesiculating agent, was dissected as function of its chemical structure. This natural product induces irreversible vesiculation of the Golgi membranes and blocks protein transport at the level of the Golgi. The Golgi localization and fragmentation effects of 7 depend on the presence of the perhydroindane core, while the irreversibility of ...

Chemical Studies on Sludge Digestion

Chemical Studies on Bacterial Agglutination

1. A method, conforming to the criteria of quantitative analytical chemistry, is described for the estimation of the agglutinin content of antisera. Examples are given of the application of the method to various antipneumococcus sera. 2. This new, absolute method is discussed with regard to its relation to the commonly used relative methods.

Chemical Studies on Intestinal Infantilism

In three cases of intestinal infantilism, the excretion of nitrogen in the urine per square meter of body surface was low. The heat radiation was normal. In spite of the fact that the absolute quantity of nitrogen was low, the distribution of nitrogen and sulphur among the various nitrogen and sulphur constituents of the urine was in the normal ratio. The ammonia excretion was normal. The ether...

Chemical studies on polymyxin B.